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Fundamentals of Molecular Biology

  •  Units 4
  •  Lessons 25
  •  No. of Downloads 599
  •  Course Type Post Graduate
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Syllabus

Historical developments of molecular biology; Nucleic acids as genetic material; Chemistry, structure and properties of DNA and RNA.

Historical developments of molecular biology

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Nucleic acids as genetic material

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Chemistry and structure of DNA and RNA

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Physical and chemical properties of DNA

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RNA structure function and types

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Syllabus

Genome organization in prokaryotes and eukaryotes; Chromatin structure and function; DNA replication; DNA polymerases, topoisomerases, DNA ligase, etc; Molecular basis of mutations; DNA repair mechanisms.

GENOME ORGANISATION OF PROKARYOTES AND EUKARYOTES

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Structure of Chromatin and function

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DNA REPLICATION

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Molecular basis of mutation and Repair

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Syllabus

Transcription process; RNA processing; Reverse transcriptase; RNA editing; Ribosomes structure and function; Organization of ribosomal proteins and RNA genes; Genetic code; Aminoacyl tRNA synthases.

TRANSCRIPTION IN PROKARYOTES

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Trancription in eukaryotes

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RNA processing in eukaryotes

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RNA editing

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Ribosome structure and function

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rRNA processing

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tRNA synthesis

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Syllabus

Translation and post-translational modifications; Operon concept; Attenuation of trp operon; important features of gene regulation in eukaryotes.

Messenger RNA and translation

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Transfer RNA and tRNA synthetase

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Ribosomes

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Translation

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Post-translational modifications

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Gene regulation in prokaryotes

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Lac operon

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Trp operon

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Gene regulation in eukaryotes

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